Grey's Anatomy is a hospital drama that focuses on Meredith Grey (Ellen Pompeo), one of several third year residents at a Seattle Grace hospital. Along with her colleagues, Meredith struggles to maintain relationships while staying sharp at work.
The professional roles and real lives of a diverse group of surgeons collide unexpectedly in this Golden Globe-winning ABC television drama. As a third-year resident at Seattle Grace Hospital, Meredith Grey (Ellen Pompeo) tries hard to live up to the reputation of her legendary surgeon mother while hiding the fact that her mom now suffers from Alzheimer's disease. As if life weren't complicated enough, Meredith also marries boss, Derek Shepherd (Patrick Dempsey). Meredith's friend and rival Cristina Yang (Sandra Oh) finds herself in a romance with 'army man' Owen Hunt (Kevin McKidd) how came to Seattle Grace from Afghanistan were he worked as a doctor. As for Meredith and Cristina's fellow residents (some not so much)-- Isobel "Izzie" Stevens (Katherine Heigl) and Alex Karev (Justin Chambers) -- they've got problems of their own. Izzie does not want to be judged by her underwear-model past and works hard but when she gets cancer, she gets fired and leaves her husband Alex. Alex is still better at bedding the ladies than bedside manner after his wife leaves and is trying to get over the grief. When Merediths little sister 'little grey' or Lexie Grey (Chyler Leigh) joined the picture in season 4 and is dating 'McSteamy' Mark Sloan (Eric Dane) who was Derek Shepherd's best friend in New York before he slept with Addison Montgomery-Shepherd (Kate Walsh [who now stars in the show Private Practice]) who was married to Derek (Addison and Derek finally divorced in Season 2). Arizona Robbins (Jessica Capshaw) turns out to be gay and now Callie Torres (Sara Ramirez) is her partner. All eight residents still answer to the roar of senior resident Miranda Bailey (Chandra Wilson), affectionately known as "the Nazi." But even Dr. Bailey jumps to it when Chief of Surgery Richard Webber (James Pickens Jr.) is on the scene. But there is one thing you must remember "Medicine nor relationships can be defined in black and white. Real life only comes in shades of grey."
The doctors split into teams for a risky surgery involving conjoined twins. Meanwhile, Teddy questions Cristina about Henry's surgery; Bailey enlists Meredith to be a buffer between her and Ben, who's pressuring her to r...
As the human wreckage from a serious auto accident preoccupies the doctors, Teddy (who's unaware that Henry has died) calls on Cristina to help with a patient; and Lexie works alongside Mark's new girlfriend, Julia, duri...
Henry is sent to the OR for emergency surgery while Teddy's away; Meredith and Derek receive news about Zola; Callie and Jackson are blamed for their patient's post-op complications; and Meredith and Alex treat an ailing...
George's mother (Debra Monk) returns to Seattle Grace after undergoing a botched surgery at another hospital, and the doctors wax nostalgic about George. Meanwhile, a harvested heart continues to beat outside its body; a...
Owen tries to teach the doctors a lesson in teamwork when he signs them up for a baseball league; Lexie can't hide her jealousy when she sees Mark with another woman; Alex fights to keep baby Zola from being transferred ...
fter being blackballed by most of the surgeons, Meredith uses Lexie to spark Derek's interest in her patient's rare brain tumor case and, in secret, gives guidance to April with Bailey's clinical trial; Callie's wish for...
Jackson's mother (Debbie Allen), a renowned surgeon, arrives to perform a groundbreaking transplant; Alex and Arizona are hamstrung by confidentiality issues when a familiar patient turns up in the ER; a love-struck Tedd...
The doctors of Seattle Grace are called upon to man up when a stampede at a comic book convention causes an influx of colorful characters in the ER blurring the lines of fantasy and reality; Mark shows his softer side wi...
The chief makes a career-changing decision; Cristina and Owen try to put their relationship on an even keel; and April continues to struggle in her new role. Meanwhile, the fifth-year residents finally get a shot at thei...
news of Meredith and Derek's unsteady relationship raises a red flag for Zola's adoption counselor; Alex quickly realizes that he has become the outcast of the group after ratting out Meredith; and Cristina makes a tough...
the fifth-year residents return for the first day of a year that will make or break their careers: Meredith faces the consequences of tampering with Derek's clinical trial and is terminated at the hospital; April tries t...
Meredith's fertility treatments start affecting her eyesight; Mark talks to Callie and Arizona about his role as a father; April learns more about Dr. Stark (Peter MacNicol).
Meredith volunteers to run the ER for a night in hope of proving that she is chief-resident material; Bailey and Eli (Daniel Sunjata) get into mischief; Adele comes to the hospital as a patient.
Meredith and Lexie's father returns to Seattle Grace with stomach pains and a new girlfriend; Alex butts heads with the new OB; Mark bribes Jackson for information on Lexie.
Meredith feels left out when Derek breaks ground on his clinical trial; Bailey's new idea does not go over well with the Chief; Callie irritates her new obstetrician (Rachael Taylor).
Arizona tries to reconcile with Callie, who has big news to share; Teddy faces an important decision; the residents receive new interns; the Chief makes an announcement.
A gunman opens fire at a local college, sending mass casualties to the hospital; Arizona's return is not warmly received.
Concerned about Cristina, Derek takes her on a fishing trip; Teddy directs her efforts and compassion toward a dying patient (Scott Foley) without the proper insurance to seek treatment.
Derek and the attendings go out to celebrate when he gets the grant he needs for his clinical trial; Meredith and Alex must fend for themselves during the night shift.
A team of doctors tries to save the life of a political figure from the Middle East; Cristina decides to decorate her new place and throw a housewarming party; Alex shows up late to his first day of rounds with the new p...
Owen puts the residents through a rigorous trauma certification drill; Cristina is left alone to monitor an ill lung transplant patient.
A documentary crew visits the hospital six months after the shooting to document the road to recovery for doctors and patients; Meredith helps Cristina put on a brave face for the cameras.
As part of their training, Seattle Grace's residents are put in charge; the attending surgeons compete for a million-dollar grant.
Derek and Meredith visit the obstetrician and receive disturbing news; Lexie notices April and Meredith growing closer; Jackson tries to get ahead in the operating room.
Issues surface when Derek's estranged sister, Amelia (Caterina Scorsone), visits unexpectedly; Meredith and Derek continue to try to ease Cristina back into surgery.
Meredith finally tells Derek about her pregnancy and miscarriage; during a surgery, Cristina experiences PTSD; Bailey won't let Alex operate until he has the bullet in his chest removed.